July 2005 researchers pinpoint genes that drive spread of breast cancer to lungs search for a special 'genetic endowment' snares new cancer candidates howard hughes medical institute researchers have identified a telltale set of genes that causes breast cancer to spread and grow in the lungs, where cancer cells often flourish with lethal consequences. generic viagra canada The researchers said that the genes are more than markers that identify the presence of metastatic cancer. These genes are mediators that enable fragments of breast cancer tumors to take root in the lungs. The scientists are hopeful that their research will give clinicians a new set of molecular tools to test tumor biopsies for the activity of these specific genes. classicmotocrossimages.com/mbs-viagra-for-sale-generic-im/ This, in turn, should help guide treatment by permitting the early diagnosis of breast cancers that will ultimately metastasize to the lung. The genes that have been identified produce proteins that may move to the top of the "most wanted list" of prime targets for therapies to thwart metastasis, said the study's senior author joan massagué, a howard hughes medical institute investigator at memorial sloan-kettering cancer center. Massagué and his colleagues are optimistic that their technique can be extended to other types of metastatic cancer, where it should aid in identifying genetic characteristics of metastatic tumors to aid diagnosis and treatment. Massagué, postdoctoral fellow andy j. viagra coupon Minn, and graduate student gaorav p. Gupta, led the research team that published its findings in the july 28, 2005, issue of the journal nature. 1000 ways die too much viagra Until now, researchers had taken a largely ad hoc approach to identifying genes that might influence how breast cancer spreads. viagra samples Such studies usually involved overactivating individual candidate genes and observing whether that change in activity affected the cancer's ability to spread. Such piecemeal studies did not yield a comprehensive, unbiased picture of the broad genetic changes that drive metastasis, according to massagué. More recent advances, including large-scale surveys of gene activity, have revealed that a tumor's metastatic potential can be identified and defined as a characteristic genetic signature that reflects gene activity in primary tumors. viagra canada online But those techniques only go so far, said massagué. prescription viagra for women Those signatures are useful markers of metastasis, but they do not necessarily reveal the identity of specific genes that drive the metastatic process, he said. generic viagra online In earlier studies in mice, massagué and his colleagues pioneered a novel approach that led to the identification of a "toolbox" of genes active in metastatic bre. viagra dosage duration canadian pharmacy viagra Faircrest Heights Community Association

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